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Tang Lab

Discovering novel immunotherapies through innovative translational research

Imaging Islet cellsThe immune system safeguards our bodies against infections and cancers, but also causes autoimmuine diseases and rejection of transplanted organs.  One of the fundamental properties of the immune system is the ability to regulate its own activities; this self-control prevents it from attacking healthy tissues and compels it to contract after successful elimination of the eliciting pathogens.  Our research seeks to better understand the mechanisms of immunoregulation, with the hopes of applying it to the prevention of transplant rejection and diabetes. 

Recent Publications

Brennan TV, Jaigirdar A, Hoang V, Hayden T, Liu FC, Zaid H, Chang CK, Bucy RP, Tang Q, Kang SM
Preferential priming of alloreactive T cells with indirect reactivity.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, Apr-01-2009; 94: 709-18
Melli K, Friedman RS, Martin AE, Finger EB, Miao G, Szot GL, Krummel MF, Tang Q
Amplification of autoimmune response through induction of dendritic cell maturation in inflamed tissues.
Journal of immunology (Baltimore, Md. : 1950), Mar-01-2009; 1825: 2590-600.
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